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Modafinil: Know Its Side Effects for Safety

Modafinil is categorized as Schedule IV controlled substance, which means that it can’t be legally obtained without the prescription of your doctor. As indicated by the United States Drug Enforcement Agency, the pills under this classification are believed to have a very low potential for abuse or addiction (physical dependence). Nonetheless, there does appear to be some study to suggest that Provigil online might have a potential for abuse or addiction (physical dependence). Based on a study done by Teva Pharmaceuticals, 11% of partakers in clinical trials reported experiencing nausea and headaches, while others suffer from negative side effects such as gastrointestinal problems, dizziness, anxiety, diarrhea, and nervousness.

Rare occurrences have been reported of more serious side effects that include skin rashes and other symptoms that are allergy-related. Since its initial date of marketing, the US Food and Drug Administration received 6 cases of severe side effects related to Modafinil such as DRESS syndrome, toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome (SJS), and erythema multiforme (EM), involving pediatric and adult patients. The FDA issued a relevant alert. In the same alert, the group also noted that multi-organ hypersensitivity reactions and angioedema have also been reported in post-marketing experiences.

In 2007, the FDA ordered Cephalon to change the Provigil Modafinil online UK leaflet in bold-face print of various serious and potentially fatal conditions attributed to Modafinil use, including SJS, DRESS syndrome, and TEN. The long-term effectiveness and safety of Modafinil have not yet been determined. Modafinil may have an adverse effect on hormonal contraceptives for up to a month after discontinuation.

Addiction and Abuse Potential 

The abuse and addiction liabilities of Modafinil are very low. It shares biochemical functions with addictive stimulant pills. Other studies have reported it to have similar mood-elevating properties, although to a lesser extent. Monkeys will self-administer Modafinil if they have been previously trained to be self-administered cocaine. Even if Modafinil doesn’t produce reinforcing effects in mice at doses that are equivalent to those used medically in humans, it does so at higher doses. Very rare case reports of Modafinil abuse exist. As such, Modafinil is categorized by the United States FDA as a Schedule IV controlled substance, the category of pills with valid medical uses and low but drastic addiction potential.

Modafinil: Know Its Side Effects for Safety

Psychological Dependence 

Psychological dependence upon Modafinil has only been noted in studies involving daily overdoses for an extended span of time. Reported withdrawal symptoms include insomnia, anxiety, lethargy, and anhedonia.

Tolerance and Psychiatric Reactions 

Large-scale studies have found no evidence of tolerance with Modafinil at therapeutic doses even with prolonged use (for 40 weeks and as long as three years). Modafinil-associated psychiatric reactions have occurred in those with or without a pre-existing history.

Modafinil use is becoming popular with students as the result of its concentration-enhancing abilities. This kind of use may result in more reports of people who take this pill being diagnosed with substance use disorders due to more serious Modafinil use. As most of the studies indicate it has a low potential for addiction, Modafinil has been suggested as being potentially useful in treating people recovering from addiction to cocaine and other drugs. For More Help, read trusted sources.

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Modafinil: Know Its Side Effects for Safety